Combined agonism of nutrient receptors GPR40 and GPR119 with K-757 and K-833 results in weight loss and blood pressure reductions in obese subjects without type 2 diabetes mellitus

We’re proud to share that Christopher Romero, MD, PhD, FACP, Medical Director at Headlands Research and Principal Investigator at Headlands Research Brownsville, is a co-author on a publication exploring the co-agonism of the GPR40 and GPR119 nutrient receptors.

The study, published in Diabetes, Obesity and Metabolism, found that co-administration of K-757 and K-833 led to significant increases in satiety hormones and reductions in both weight and blood pressure—highlighting promising potential beyond glucose control.

Read more about the findings in Diabetes, Obesity and Metabolism.